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Past, present and future of applied radiobiology

Year: 2012
Type: article
Abstract: Radiobiology as a scientific discipline was created at the beginning of the 20th century and its development was connected with progress of radiotherapy (RT). The main aim of radiation biology is to translate the findings from basic research into clinical practice and aim to personalize anticancer treatment. In the paper the historical outline of radiobiology is presented, divided arbitrarily into four periods: cellular radiobiology (1950), experimental radiobiology (1970–1990), applied radiobiology (1990–2000) and molecular radiobiology (2001– present). The most significant achievements which have had an influence on the development of radiation oncology in these periods are presented. Also the evolution of radiobiological prognostic and predictive tests applied in radiation oncology with the aim to individualize anticancer treatment are described, with a perspective on their development in the nearest future.
Language: English
Field: Medicine
Open Access status: green
OpenAlex ID: W2623429572
FWCI:
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