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Role of Immune Cells in Acute Kidney Injury and Repair

Year: 2017

Type: article

Abstract: Acute kidney injury (AKI) is a significant problem in both native and transplant kidneys. There have been significant advances in understanding the role of immune cells in the early injury and repair from AKI. In this brief review, we aim to update information on the pathophysiologic impact of various immune cells in AKI, with special emphasis on repair. An improved understanding of the AKI immunopathology will lead to new therapies that prevent AKI, accelerate repair, and prevent the progression of AKI to chronic kidney disease.

Source: The Nephron journals/Nephron journals

DOI: 10.1159/000477181

Authors: Sul A Lee, Sanjeev Noel, Mohanraj Sadasivam, Abdel R.A. Hamad, Hamid Rabb

Institution: Johns Hopkins University

Language: English

Topic: Acute Kidney Injury Research

Subfield: Nephrology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases