Work

Transition-Metal Catalysis of Nucleophilic Substitution Reactions: A Radical Alternative to SN1 and SN2 Processes

Year: 2017

Type: article

Abstract: 2) have limited scope and are not generally amenable to enantioselective variants that employ readily available racemic electrophiles. Radical-based pathways catalyzed by chiral transition-metal complexes provide an attractive approach to addressing these limitations.

Source: ACS Central Science

DOI: 10.1021/acscentsci.7b00212

Author: Gregory C. Fu

Institution: California Institute of Technology

Language: English

Topic: Asymmetric Synthesis and Catalysis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

Funder: National Institute of General Medical Sciences

Awards: G1839701573, G2605642020, Metal-Catalyzed Coupling Reactions