Work

Phase-contrast tomography of sciatic nerves: image quality and experimental parameters

Year: 2017

Type: conference-paper

Abstract: We present propagation-based phase-contrast tomography of mouse sciatic nerves stained with osmium, leading to an enhanced contrast in the myelin sheath around the axons, in order to visualize the threedimensional (3D) structure of the nerve. We compare different experimental parameters and show that contrast and resolution are high enough to identify single axons in the nerve, including characteristic functional structures such as Schmidt-Lanterman incisures.

Source: Journal of Physics Conference Series

DOI: 10.1088/1742-6596/849/1/012001

Authors: M Töpperwien, M Krenkel, T Ruhwedel, W Möbius, A Pacureanu, P Cloetens, T Salditt

Institutions: University of Göttingen, Max Planck Institute of Experimental Medicine, European Synchrotron Radiation Facility

Language: English

Topic: Advanced X-ray Imaging Techniques

Subfield: Radiation

Field: Physics and Astronomy

Domain: Physical Sciences

Open Access status: diamond

Funder: Deutsche Forschungsgemeinschaft

OpenAlex ID: W2624762392

FWCI: 4.583

Cites: 10

Cited by: 10

Related to: 10