The GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature
Year: 2017
Type: article
Study design: Observational Study
Abstract: variant is a common genetic polymorphism that modulates GH responsiveness throughout the life span and positively affects male longevity.
Source: Science Advances
Institutions: Albert Einstein College of Medicine, Harvard University, Inserm, Bicêtre Hospital, University of Vermont, University of Southern California, University of Maryland, Baltimore, University of Haifa, University of Washington, Fred Hutch Cancer Center, United States Department of Veterans Affairs, Baltimore VA Medical Center
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $4,500
Funders: Glenn Foundation for Medical Research, Johns Hopkins University, Institut National de la Santé et de la Recherche Médicale, Novo Nordisk, National Institutes of Health, National Institute on Aging, National Heart, Lung, and Blood Institute, National Human Genome Research Institute, National Institute of Diabetes and Digestive and Kidney Diseases
Awards: G1220223050, G1275353700, CORONARY HEART DISEASE AND STROKE, Epigenetic Profiling in Healthy Aging and Exceptional Longevity, G1909643007, G2194386449, G2399858043, G277826483, G2800149121, G2873320358, G3086232184, GENOTYPING FOR LOCATING HUMAN DISEASE GENES, G3447021296, CENTRAL BLOOD ANALYSIS LABORATORY FOR CHS, G423252844, G4498387036, G454583138, G4987078009, G5359555627, A family of novel mitochondrially-encoded peptides and their role in aging, G5780424650, CHS Events Follow-up Study, G6226795708, Einstein's Nathan Shock Center of Excellence in Basic Biology of Aging, Dysregulation of Glucose Homeostasis in Aging, CHS RETINAL READING CENTER, G777822606, Diabetes Research and Training Center, G7999488110, CHS-Transition Phase -268055222, G9000018859, G9000027259, G9000036580, G9000069887, G9000086042, G9000145448, G9000155493, G9000159977, G9000169005, G9000239991, G9000294005, NYR-Diabetes Research Center (NYR-DRC), Older Americans Independence Center, G905887895, G960597250
OpenAlex ID: W2624809407