Work

Biocompatibility of normal human urothelial (NHU) and urinary tract-derived smooth muscle (USM) cells grown on two and three dimensional (poly (lacticco-glycolic) acid (PLGA) scaffolds

Year: 2006

Type: article

Abstract: INTRODUCTION: The main function of the bladder as a low pressure storage reservoir for urine can be severely compromised as a result of severe dysfunction, trauma, cancer and congenital abnormalities. Tissue engineering strategies are consequently being developed in an attempt to rebuild and surgically repair the bladder. This investigation concentrates on the development of synthetic biomaterials as scaffolds for bladder repair/reconstruction. We report the preparation of non-porous two dimensional films and porous three dimensional foams and assess their biocompatibility in terms of supporting the adhesion and growth of NHU and USM cells.

Source: European Cells and Materials

Authors: J. Pettit, Géraldine Rohman, Françoise Isaure, Neil R. Cameron, Jennifer Southgate

Institutions: University of York, Durham University

Language: English

Topic: Tissue Engineering and Regenerative Medicine

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,000

OpenAlex ID: W262544818