Inflammatory Markers and Stroke: The Relationship
Year: 2012
Type: article
Study design: Observational Study
Abstract: Objective: To evaluate the relationship between markers of inflammation markers, Creactive protein (CRP) and leukocytes, and stroke. Design: A prospective clinical study. Setting: Al-Sadr Teaching Hospital, Basrah, Iraq Patients and Methods: In this prospective study,73 patients (42 males and 31 females) with acute stroke and 75 control subjects (45 males and 30 females) were included. CRP concentration, leukocyte count, fasting blood glucose (FBG), total cholesterol (TC), triglycerides (TG ), high density lipoproteincholesterol (HDL-C), and low density lipoprotein-cholesterol (LDL-C) level were determined in patients and controls. Results: CRP and leukocytes were significantly higher among male patients with acute stroke compared to controls (p 0.05). As shown in Table 2. CRP and leukocytes were significantly higher among male patients with acute stroke compared to controls (p<0.001). In addition FBG, TC, TG and LDL-C concentrations were significantly higher while HDL-C level was significantly lower among patients compared to control subjects (p<0.001). The results in females are presented in Table 3. Similarly, female patients showed significantly higher CRP and leukocytes compared to female controls (P<0.05 and P<0.001 respectively). Also, FBG, TC, TG and LDL-C concentrations were significantly higher whereas HDL-C level was significantly lower among patients compared to controls (p<0.001). Table 1. Characteristics of stroke patients and control subjects. Characteristic Male patients (n=42) Male controls (n=45) Female Patients (n=31) Female controls (n=30) Age (years) 56.4 (11.8) 53.1 (10.2) 54.9 (9.7) 51.4(11.1) BMI (Kg/m) 26.4 (5.1)** 23.9 (3.0) 27.9 (5.5)** 24.4(3.0) SBP (mm.Hg) 161.3 (24.8)*** 124.9 (11.3) 157.6 (25.5)*** 121.8(12.8) DBP (mm.Hg) 100.5(10.9)*** 83.3 (7.8) 98.4 (10.6)*** 79.7(9.7)
Source: Kufa Medical Journal
Authors: Salman K. Ajlan, M Chb, Mehta Sc, Assist. Professor د. سلمان كاظم عجلان
Language: English
Subfield: Clinical Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2627056472