Work

Self-assembly of bioactive peptides, peptide conjugates, and peptide mimetic materials

Year: 2017

Type: review

Abstract: Molecular self-assembly is a multi-disciplinary field of research, with potential chemical and biological applications. One of the main driving forces of self-assembly is molecular amphiphilicity, which can drive formation of complex and stable nanostructures. Self-assembling peptide and peptide conjugates have attracted great attention due to their biocompatibility, biodegradability and biofunctionality. Understanding assembly enables the better design of peptide amphiphiles which may form useful and functional nanostructures. This review covers self-assembly of amphiphilic peptides and peptide mimetic materials, as well as their potential applications.

Source: Organic & Biomolecular Chemistry

DOI: 10.1039/c7ob01092c

Authors: Charlotte J. C. Edwards-Gayle, Ian W. Hamley

Institution: University of Reading

Language: English

Topic: Supramolecular Self-Assembly in Materials

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $3,676

Funders: Diamond Light Source, University of Reading, Engineering and Physical Sciences Research Council