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Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment

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Year: 2016
Type: article
Source: Nature
DOI: 10.1038/nature20131
Authors: Lei Dong, Wen-Mei Yu, Hong Zheng, Mignon L. Loh, Silvia T. Bunting, Melinda Pauly, Gang Huang, Muxiang Zhou, Hal E. Broxmeyer, David T. Scadden, Cheng-Kui Qu
Institutions: Emory University, Children's Healthcare of Atlanta, University of California, San Francisco, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Indiana University Indianapolis, Indiana University School of Medicine, Harvard University, Massachusetts General Hospital, Harvard Stem Cell Institute
Language: English

Topic: Protein Tyrosine Phosphatases
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: National Heart, Lung, and Blood Institute, National Institute of Diabetes and Digestive and Kidney Diseases
Awards: Mechanisms of Synergistic Regulation of Stem/Progenitors, Role of the Hypoxia-Inducible Factor-1alpha in Myelodysplastic Syndromes, Metabolic regulation of hematopoietic stem cells, Germline mutations of PTPN11 (SHP2) in the stem cell microenvironment
OpenAlex ID: W2541514381
FWCI: 13.38
Cites: 39
Cited by: 260
Related to: 10
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