Coeloglossum viride var. bracteatum extract protects against amyloid toxicity in rat prefrontal cortex neurons.
Year: 2010
Type: article
Abstract: CE is the extract from Coeloglossum viride var.bracteatum, a plant widely used as a traditional medicine in the Southwest China, such as Tibet. The effects of CE against amyloid toxicity in cell culture were examined in the present study. The results indicate that CE can protect against amyloid beta (Abeta)(25-35)-induced cytotoxicity in rat primary prefrontal cortex neurons. Bcl(2) and Csp3 activation may be involved in CE protection. CE could be a promising candidate for amyloid-based Alzheimer's disease (AD) prevention or therapy.
Source: PubMed
Authors: Xiao-Yan Qin, Jia Cui, Yan Zhang
Institutions: Minzu University of China, Peking University
Language: English
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W269405971