Work

Safety, Phamacokinetics (PK), Pharmacodynamics (PD) and Preliminary Activity in Acute Leukemia of Ory-1001, a First-in-Class Inhibitor of Lysine-Specific Histone Demethylase 1A (LSD1/KDM1A): Initial Results from a First-in-Human Phase 1 Study

Year: 2016

Type: article

Study design: Clinical Trial

Source: Blood

DOI: 10.1182/blood.v128.22.4060.4060

Authors: Tim Somervaille, Olga Salamero, Pau Montesinos, Christophe Willekens, Jose Antonio Perez Simon, Arnaud Pigneux, Christian Recher, Rakesh Popat, Cesar Molinero, Christina Mascaro, Tamara Maes, Francesc Bosch

Institutions: The Christie NHS Foundation Trust, Vall d'Hebron Hospital Universitari, Hospital Universitari i Politècnic La Fe, Institut Gustave Roussy, Fondation Gustave Roussy, Hospital Universitario Virgen del Rocío, Centre Hospitalier Universitaire de Bordeaux, Hôpital Cardiologique du Haut-Lévêque, Centre Hospitalier Universitaire de Toulouse, Institut universitaire du cancer de Toulouse Oncopole, University College London Hospitals NHS Foundation Trust, Oryzon Genomics (Spain)

Language: English

Topic: Acute Myeloid Leukemia Research

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W2726227284

FWCI: 5.369

Cites:

Cited by: 46

Related to: 10