Polycystic ovarian syndrome: the correlation between the LH/FSH ratioand disease manifestations
Year: 2007
Type: article
Study design: Observational Study
Abstract: Objectives: to study the correlation and association among LH / FSH\nratio, BMI and clinical manifestations of Polycystic Ovarian Syndrome\n(PCOS). Setting: Institution of Infertility Treatment and Embryo\nResearch. Study design: A cross sectional descriptive study. Materials\nand Methods: One hundred and seven infertile women with PCOS were\nincluded according to their menstrual history (Amenorrhea or\noligomenorrhea) and/or presence of hirsutism. All of them were\nsubjected to vaginal ultrasound to confirm the presence of polycystic\novary. Body Mass Index (BMI) assessed to be included in the\ncorrelations. Blood collected twice (4-5 days interval) from each\nattendant to measure their serum FSH, LH & mean LH/FSH ratio\nobtained. The resulted data were arranged in tables and subjected for\nstatistical study using correlation analysis. Results: The\ncharacteristics of women recruited, showed that 59.81% of them were\n25-32 years old, and 63.55% of them were over weight or obese\n(BMI>25). Besides the infertility, the commonest second complaint\nwas hirsutism (64.49%) While oligomenorrhea is prevalent in 43.93%,\namenorrhea in 22% and only minority (6.56%) have regular menses. The\nrelationship between study variables as assessed by correlation\nanalysis revealed no statistical significant correlation among LH/FSH\nratio, BMI and other manifestations (hirsutism and oligomenorrhea).\nConclusion: No significant statistical correlation is found between\nLH/FSH ratio, BMI, menstrual pattern and hirsutism. This disproves the\ntraditional concept about PCOS which regards that the heavier the\npatient is the higher the LH or the worst manifestations.
Author: Abdulrazak H. Alnakash
Language: English
Subfield: Reproductive Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2727893170