The Influence of Bmi From Childhood to Adulthood on Cognition and Physical Performance in Middle Age
Year: 2017
Type: conference-abstract
Abstract: It is unclear whether BMI from childhood and young adulthood predicts cognition and physical performance in mid-life. Using data from Bogalusa Heart Study (n=880; mean (SD) age at baseline=10.6 years (2.8), BMI=18.1 (3.6), 64.1% female, 33.0% black), we examined the longitudinal association of BMI, measured at recurrent clinic visits, with cognition (the sum of standardized scores on 11 validated neuropsychological tests) and physical performance (the Short Physical Performance Battery [SPPB]). A one-unit increase in BMI was associated with a decrease of 0.14 points (p<0.001) on the SPPB and of 0.001 (p=0.02) standard deviations in the global cognitive z-score in multivariable GEE models. The association disappeared in whites but remained for blacks when analyzed separately, suggesting a possible difference by race. Models investigating rate of change of BMI provided similar results, suggesting that interventions targeting BMI reduction or preventing obesity in childhood may improve cognition or physical function in middle age.
Source: Innovation in Aging
Authors: P. Stuchlik, B.D. Pollock, T. Shu, J.M. Guralnik, J. Gustat, W. Chen, E.W. Harville, L. Bazzano
Institutions: Tulane University, University of Maryland, Baltimore
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,977
OpenAlex ID: W2729132897