Year: 2017
Type: article
Abstract: Mg2+ is an essential mineral with pleotropic impacts on cellular physiology and functions. It acts as a cofactor of several important enzymes, as a regulator of ion channels such as voltage‐dependent Ca2+ channels and K+ channels and on Ca2+‐binding proteins. In general, Mg2+ is considered as the main intracellular antagonist of Ca2+, which is an essential secondary messenger initiating or regulating a great number of cellular functions. This review examines the effects of Mg2+ on mitochondrial functions with a particular focus on energy metabolism, mitochondrial Ca2+ handling, and apoptosis.
DOI: 10.1155/2017/6797460
Authors: Ivana Pilchova, Katarina Klacanova, Zuzana Tatarkova, Peter Kaplan, Peter Racay
Institution: Comenius University Bratislava
Language: English
Subfield: Nutrition and Dietetics
Field: Nursing
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $2,680
Awards: G1794509337, G4845132850
OpenAlex ID: W2732080466