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Inactivation of the Mgat1 Gene in Oocytes Impairs Oogenesis, but Embryos Lacking Complex and Hybrid N-Glycans Develop and Implant

Year: 2005

Type: article

Abstract: The ⌬ label should read "ϩ, neo."Page 9927, Fig. 5 legend, lines 7 to 9: should read "cultured outgrowths.The left gel shows that the floxed Mgat1 F allele (F) had been deleted in each embryo and that each embryo carried an Mgat1 neo (neo) or Mgat1 ϩ (ϩ) allele, detected with primers PS585 and PS586 (Fig. 1).The right gel shows whether a mutant egg was fertilized by an Mgat1 ϩ or Mgat1 neo sperm, detected with primers PS91, PS92, and PS93 (Fig. 1)."

Source: Molecular and Cellular Biology

DOI: 10.1128/mcb.25.3.1214.2005

Authors: Shi, Shaolin, Williams, Suzannah A., Seppo, Antti, Kurniawan, Henry, Chen, Wei, Ye, Zhengyi, Marth, Jamey D., Stanley, Pamela

Institutions: Albert Einstein College of Medicine, Howard Hughes Medical Institute, University of California San Diego

Language: English

Topic: Glycosylation and Glycoproteins Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W2734258180

FWCI: 0.499

Cites:

Cited by: 7

Related to: 10