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Allosteric sensitization of proapoptotic BAX

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Year: 2017
Type: article
Source: Nature Chemical Biology
DOI: 10.1038/nchembio.2433
Authors: Jonathan R Pritz, Franziska Wachter, Susan Lee, James Luccarelli, Thomas E Wales, Daniel T Cohen, Paul Coote, Gregory J Heffron, John R Engen, Walter Massefski, Loren D Walensky
Institutions: Harvard University, Dana-Farber Cancer Institute, Northeastern University
Language: English

Topic: Cell death mechanisms and regulation
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: National Cancer Institute, National Institute of General Medical Sciences
Awards: Extending the applications of hydrogen exchange mass spectrometry, Medical Scientist Training Program, Dissecting the Functional Roles of Two BH3-Binding Sites on Pro-Apoptotic BAX, Dissecting and Targeting Deregulated Mitochondrial Apoptosis in Human Cancer
OpenAlex ID: W2734442873
FWCI: 2.122
Cites: 60
Cited by: 49
Related to: 10
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