Work

Sorting without a Golgi complex

Year: 2017
Type: review
Abstract: The endoplasmic reticulum-Golgi-target organelle route is one of the most studied events and has fascinated researchers for years. However, the conservative mechanism of protein sorting and delivery is now being challenged by the finding of unconventional pathways driving protein sorting and transport. Protozoa parasites are being rediscovered as good models for analyzing alternative targeting pathways, associated with their ability to adapt to diverse environments and hosts. Here, we have gathered all the available information about secretory protein trafficking in Giardia lamblia, with a focus on how this protozoan parasite is able to sort and direct proteins to different compartments in the absence of a Golgi complex.
Source: Traffic
Language: English
Subfield: Cell Biology
Open Access status: bronze
OpenAlex ID: W2735295862
FWCI: 0.191
Cites: 95
Cited by: 17
Related to: 10