Work

Statistical Methods for Recurrent Event Analysis in Cohort Studies of CKD

Year: 2017

Type: article

Abstract: Cardiovascular events, such as hospitalizations because of congestive heart failure, often occur repeatedly in patients with CKD. Many studies focus on analyses of the first occurrence of these events, and discard subsequent information. In this article, we review a number of statistical methods for analyzing ordered recurrent events of the same type, including Poisson regression and three commonly used survival models that are extensions of Cox proportional hazards regression. We illustrate the models by analyzing data from the Chronic Renal Insufficiency Cohort Study to identify risk factors for congestive heart failure hospitalizations in patients with CKD. We show that recurrent event analyses provide additional insights about the data compared with a standard survival analysis of time to the first event.

Source: Clinical Journal of the American Society of Nephrology

DOI: 10.2215/cjn.12841216

Authors: Wei Yang, Christopher Jepson, Dawei Xie, Jason A. Roy, Haochang Shou, Jesse Yenchih Hsu, Amanda Hyre Anderson, J. Richard Landis, Jiang He, Harold I. Feldman, on behalf of the Chronic Renal Insufficiency Cohort (CRIC) Study Investigators

Institutions: University of Pennsylvania, Tulane University

Language: English

Topic: Statistical Methods in Epidemiology

Subfield: Statistics and Probability

Field: Mathematics

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute of General Medical Sciences, National Institute of Diabetes and Digestive and Kidney Diseases, National Center for Research Resources, National Center for Advancing Translational Sciences

Awards: Clinical and Translational Science Institute, Continuation of the Chronic Renal Insufficiency Cohort (CRIC) Study, General Clinical Research Center, Center for Clinical and Translational Science, Michigan Institute for Clinical and Health Research (MCHR), Michigan Institute for Clinical and Health Research (MICHR), Institute for Clinical and Translational Research, Institutional Clinical and Translational Science Award, Clinical and Translational Science Award, Clinical and Translational Science Collaborative of Cleveland, Tulane COBRE for Clinical and Translational Research in Cardiometabolic Diseases, Prospective renal insufficiency cohort evaluation: PRICE, Chronic Renal Insufficiency Cohort (CRIC) Study Clinical Center, Continuation of the University of Illinois Chicago CRIC Clinical Center, Limited Competition for the Continuation of the Chronic Renal Insufficiency Cohort (CRIC) Hopkins Clinical Center, Tulane Clinical Center for Chronic Renal Insufficiency Cohort Study, Chronic Renal Insufficiency Cohort Limited competition continuation, Chronic Renal Insufficiency Cohort (CRIC) Study

OpenAlex ID: W2735319950

FWCI: 3.044

Cites: 24

Cited by: 69

Related to: 10