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Orientation-Dependent 3He Lung Imaging in an Open Access, Very-Low-Field Human MRI System

Year: 2004
Type: preprint
Abstract: Orientation-dependent imaging of human lungs is demonstrated using inhaled laser-polarized 3He gas and an open-access very-low-magnetic field (< 5 mT) MRI instrument. This prototype device employs a simple, low-cost electromagnet, with an open geometry that allows variation of the orientation of the imaging subject in a two-dimensional plane. Two-dimensional 3He images were acquired with 2 mm in-plane resolution from a subject in two orientations: lying supine, and sitting in a vertical position with one arm raised. The images show clear differences in lung shape and inhaled 3He gas distribution, consistent with the expected orientation dependence of pulmonary physiology.
Language: English
Open Access status: green
OpenAlex ID: W2735698573
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Cited by: 3
Related to: 20