Thalamocortical dysconnectivity in ASD: an analysis of the ABIDE
Year: 2016
Type: other
Abstract: ASD is defined by deficits in social interaction and communication, rigid or stereotypical behaviors, and abnormal sensory processing. The Thalamus plays a key role in gating sensory information to the cortex, modulating efferent motor signals, and regulating overall cortical activity by virtue of the sensory input it receives and dense connections with virtually all regions of the cortex. Consequently, the neuropathology of ASD may involve dysfunction of the Thalamus and its connections with the cortex. Using data from the ABIDE, a large, publically-available repository of rs-fMRI scans collected on over 1100 individuals, the goal of this study is to clarify mixed findings on thalamocortical functional connectivity in ASD.
Authors: Monica Giraldo, Carissa Cascio, Neil Woodward
Institution: Vanderbilt Psychiatric Hospital
Language: English
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W2736074602