Work

Mobile DNA in Health and Disease

Year: 2017

Type: review

Abstract: More than half the human genome is derived from transposable elements (also known as mobile DNA or “jumping genes”); some of these elements have been repurposed over time in the service of evolution. “Live” mobile elements are a rare cause of genetic disease.

Source: New England Journal of Medicine

DOI: 10.1056/nejmra1510092

Authors: Haig H. Kazazian, John V. Moran

Institutions: Johns Hopkins University, University of Michigan, Johns Hopkins Medicine, Michigan Medicine

Language: English

Topic: Chromosomal and Genetic Variations

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institute of Mental Health, National Institute of General Medical Sciences