Work

Dynamic nuclear polarization for sensitivity enhancement in modern solid-state NMR

Year: 2017

Type: review

Abstract: The field of dynamic nuclear polarization has undergone tremendous developments and diversification since its inception more than 6 decades ago. In this review we provide an in-depth overview of the relevant topics involved in DNP-enhanced MAS NMR spectroscopy. This includes the theoretical description of DNP mechanisms as well as of the polarization transfer pathways that can lead to a uniform or selective spreading of polarization between nuclear spins. Furthermore, we cover historical and state-of-the art aspects of dedicated instrumentation, polarizing agents, and optimization techniques for efficient MAS DNP. Finally, we present an extensive overview on applications in the fields of structural biology and materials science, which underlines that MAS DNP has moved far beyond the proof-of-concept stage and has become an important tool for research in these fields.

Source: Progress in Nuclear Magnetic Resonance Spectroscopy

DOI: 10.1016/j.pnmrs.2017.06.002

Authors: Aany Sofia Lilly Thankamony, Johannes J. Wittmann, Monu Kaushik, Björn Corzilius

Institution: Goethe University Frankfurt

Language: English

Topic: Advanced NMR Techniques and Applications

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $4,170

Funder: Deutsche Forschungsgemeinschaft