Work

Understanding biomaterial-tissue interface quality: combined in vitro evaluation

Year: 2017
Type: review
Abstract: One of the greatest challenges in the development of new medical products and devices remains in providing maximal patient safety, efficacy and suitability for the purpose. A 'good quality' of the tissue-implant interface is one of the most critical factors for the success of the implant integration. In this paper this challenge is being discussed from the point of view of basic stimuli combination to experimental testing. The focus is in particular on bacterial effects on tissue-implant interaction (for different materials). The demonstration of the experimental evaluation of the tissue-implant interface is for dental abutment with mucosal contact. This shows that testing of the interface quality could be the most relevant in controlled conditions, which mimic as possible the clinical applications, but consider variables being under the control of the evaluator.
Institution: Aalto University
Language: English
Subfield: Oral Surgery
Field: Dentistry
Open Access status: gold
Estimated APC paid: $1,134
Funder: Tekes
OpenAlex ID: W2739950869
FWCI: 1.433
Cites: 95
Cited by: 55
Related to: 10