Year: 2013
Type: editorial
Abstract: License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Treatment of chronic pain remains an unresolved problem in human medicine which greatly impairs quality of life and prolongs treatment. Solving this problem is difficult due to a number of mechanisms and signalling pathways through which chronic pain is generated [1]. A common underlying mechanism of chronic pain is the presence of inflammation at the site of the damaged or affected tissue. The release of proinflammatory and immunoactive substances such as cytokines, neurotrophic factors, and chemokines initiates local actions and can result in a more generalized immune response that leads to the chronic pain condition. Clinical management of chronic pain, that is, neuropathic pain after nerve injury or cancer pain in tumour invasion represents
Source: Mediators of Inflammation
DOI: 10.1155/2013/783235
Author: Metoda Lipnik-Stangelj
Institution: University of Ljubljana
Language: English
Subfield: Physiology (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,040
OpenAlex ID: W2087902742