Identification of the viral molecules recognised by influenza specific human cytoxic T lymphocytes.
Year: 1987
Type: article
Abstract: Human cytotoxic T cells specific for influenza A virus were tested for recognition of each of the ten influenza A virus proteins expressed in target cells using recombinant vaccinia viruses. They recognized the matrix M1, polymerase PB2, and nucleoproteins of influenza virus in association with MHC class I antigens. These internal viral proteins were seen by CTL in conjunction with one or more of the available dependent HLA gene products. There was no detectable recognition of influenza virus surface glycoproteins in target cells.
Source: Apollo (University of Cambridge)
DOI: 10.17863/cam.11877
Authors: Smith, GL, Gotch, FM, McMichael, AJ, Moss, B
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2740201103