Białka szoku termicznego w reumatoidalnym zapaleniu stawów: przyjaciel czy wróg?
Year: 2011
Type: article
Abstract: Rheumatoid arthritis (RA) is one of the most common rheumatic diseases in the world. RA is a progressive and incurable systemic connective tissue disease with autoimmune background. Numerous reports indicate that the highly evolutionarily conserved heat shock proteins (HSP) are able to interact with the immune system. Recent research has shown that HSP play an important role in the regulation of chronic inflammation in RA, with the majority of information concerning the role of proteins belonging to the HSP70, HSP60 and HSP40 classes. This paper presents recent views on the role of HSP in the development of rheumatic diseases, as well as the potential for application of HSP in immunotherapy of patients suffering from RA.
Authors: Stefan Tukaj, Barbara Lipińska
Institution: University of Gdańsk
Language: Polish
Topic: Heat shock proteins research
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W2402699618