Diffuse optical localization of blood vessels and 3D printing for guiding oral surgery
Year: 2017
Type: article
Abstract: Diffuse optical imaging through centimeters of tissue has emerged as a powerful tool in biomedical research. However, applications in the operating theater have been limited in part due to data set requirements and computational burden. We present an approach that uses a small number of optical source-detector pairs that allows for the fast localization of arteries in the roof of the mouth and has the potential to reduce complications during oral surgery. The arteries are modeled as multiple-point absorbers, allowing localization of their complex shapes. The method is demonstrated using a printed tissue-simulating mouth phantom. Furthermore, we use the extracted position information to fabricate a custom surgical guide using 3D printing that could protect the arteries during surgery.
Source: Applied Optics
DOI: 10.1364/ao.56.006649
Institutions: Purdue University West Lafayette, KLA (United States)
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: Towards Deep Tissue Imaging of Fluorescence Resonance Energy Transfer Parameters, CIF: Small: Fast In Vivo Optical Imaging in the Heavily and Weakly Scattering Regimes, CIF - Small: High Resolution Computational Imaging with Motion in Spatially Varying Fields, Optical Imaging of Targeted Anti-Cancer Drug Delivery Kinetics
OpenAlex ID: W2742959595