Work

Strategies for transitioning macrocyclic peptides to cell-permeable drug leads

Year: 2017

Type: review

Source: Current Opinion in Biotechnology

DOI: 10.1016/j.copbio.2017.07.007

Authors: Louise J Walport, Richard Obexer, Hiroaki Suga

Institution: The University of Tokyo

Language: English

Topic: Chemical Synthesis and Analysis

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Japan Society for the Promotion of Science, Japan Science and Technology Agency, Horizon 2020, Core Research for Evolutional Science and Technology, H2020 Marie Skłodowska-Curie Actions

Awards: G3516210569, Generation of minimal peptide catalysts based on the macrocyclic scaffold, Application of peptide screening technology for identification of substrates of the Jumonji-C histone demethylases, 薬剤活性向上した大環状ペプチドを開発する新規戦略

OpenAlex ID: W2743372157

FWCI: 0.88

Cites: 75

Cited by: 74

Related to: 10