Work

The anticancer activity of Cyathula prostrata on two malignant cell lines

Year: 2010
Type: dissertation
Abstract: were investigated with the aid of fluorescently labelled (FITC) antibodies with analysis using flow cytometry. No change in p21 levels was observed in response to treatment with the extract for up to 48 h. Cell cycle arrest in G1 was therefore not induced by this cyclin-CDK inhibitor. Increase in caspase-8 activation was observed in response to treatment with the extract with no cyt-c release from the mitochondria. The lack of cyt-c release was due to no change in mitochondrial membrane potential
Language: English
Subfield: Plant Science
Open Access status: green
OpenAlex ID: W2745961257
Cites: 73
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Related to: 10