Work

Impact of steroids on the inflammatory response after ischemic acute kidney injury in rats

Year: 2017

Type: article

Abstract: < 0.05). In contrast to the control group, the prednisolone group demonstrated no further incline of IL-18 after 24 h. The results demonstrate the importance of stretching the observation period in an ischemia-reperfusion-induced AKI setting beyond the first 24 h. Despite the demonstrated protective effects of a continuous prednisolone application, it seems that this single anti-inflammatory agent will not be able to completely suppress the inflammatory response after an ischemia-reperfusion-induced AKI.

Source: Indian Journal of Nephrology

DOI: 10.4103/ijn.ijn_40_17

Authors: J Fontana, A Vogt, A Hohenstein, U Vettermann, E Doroshenko, E Lammer, BA Yard, S Hoeger

Institutions: Heidelberg University, University Medical Centre Mannheim, Medizinische Fakultät Mannheim

Language: English

Topic: Acute Kidney Injury Research

Subfield: Nephrology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W2746079940

FWCI: 1.187

Cites: 38

Cited by: 11

Related to: 10