Carryover effects of larval exposure to different environmental bacteria drive adult trait variation in a mosquito vector
Year: 2017
Type: article
Abstract: , a major arbovirus vector breeding in both sylvatic and domestic habitats in Sub-Saharan Africa. Targeted metagenomics revealed differing bacterial communities in the water of natural breeding sites in Gabon. Experimental exposure to different native bacterial isolates during larval development resulted in significant differences in pupation rate and adult body size but not life span. Larval exposure to an Enterobacteriaceae isolate resulted in decreased antibacterial activity in adult hemolymph and reduced dengue virus dissemination titer. Together, these data provide the proof of concept that larval exposure to different bacteria can drive variation in adult traits underlying vectorial capacity. Our study establishes a functional link between larval ecology, environmental microbes, and adult phenotypic variation in a holometabolous insect vector.
Source: Science Advances
Institutions: Centre National de la Recherche Scientifique, Institut Pasteur, Department of Genomes & Genetics, Maladies Infectieuses et Vecteurs: Écologie, Génétique, Évolution et Contrôle, Centre International de Recherches Médicales de Franceville, Institut de Recherche pour le Développement, Lyon 1 Université, University of Helsinki, Université de Lyon, Ecologie microbienne
Language: English
Subfield: Insect Science
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,488
Awards: G1554707310, G1912254612, G1979782309, Organisation et montée en puissance d'une Infrastructure Nationale de Génomique, G2579310621, Contribution of gut bacterial diversity to Aedes aegypti vectorial capacity, G282427092, G4544264701, G5786005440, G705061367, G7240651115, Integrative Biology of Emerging Infectious Diseases, G7839788094, G7999552054, G8172803556, G8670608220
OpenAlex ID: W2748261468