Work

Exosomal TGF-β1 is correlated with lymphatic metastasis of gastric cancers.

Year: 2017

Type: article

Abstract: <0.01). Adding TGF-β1 neutralizing antibody partially abrogated the effects of exosomes on Treg induction. Our study showed exosomal TGF-β1 related to lymph node metastasis and the ratio of Treg cells in lymph nodes of gastric cancers. Exosomes from gastric cancer patients could induce Treg cells formation through the effect of TGF-β1.

Source: Europe PMC (PubMed Central)

Authors: Er-Yen Yen, Shi-Chuen Miaw, Jhang-Sian Yu, I-Rue Lai

Institutions: National Taiwan University, National Taiwan University Hospital

Language: English

Topic: Extracellular vesicles in disease

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2748518373

FWCI: 2.241

Cites: 29

Cited by: 73

Related to: 10