Consensus Report by the Pediatric Acute Lung Injury and Sepsis Investigators and Pediatric Blood and Marrow Transplant Consortium Joint Working Committees on Supportive Care Guidelines for Management of Veno-Occlusive Disease in Children and Adolescents: Part 2—Focus on Ascites, Fluid and Electrolytes, Renal, and Transfusion Issues
Year: 2017
Type: article
Abstract: Even though hepatic veno-occlusive disease (VOD) is a potentially fatal complication of hematopoietic cell transplantation (HCT), there is paucity of research on the management of associated multiorgan dysfunction. To help provide standardized care for the management of these patients, the HCT Subgroup of the Pediatric Acute Lung Injury and Sepsis Investigators and the Supportive Care Committee of the Pediatric Blood and Marrow Transplant Consortium, collaborated to develop evidence-based consensus guidelines. After conducting an extensive literature search, in part 2 of this series we discuss the management of fluids and electrolytes, renal dysfunction; ascites, pleural effusion, and transfusion and coagulopathy issues in patients with VOD. We consider the available evidence using the GRADE criteria.
Institutions: The University of Texas MD Anderson Cancer Center, St. Jude Children's Research Hospital, Phoenix Children's Hospital, Mayo Clinic in Arizona, Mayo Clinic Hospital, Children's Mercy Hospital, University of Missouri–Kansas City, Baylor College of Medicine, Texas Children's Hospital, University of Miami, Nationwide Children's Hospital, Cleveland Clinic, The Ohio State University, Dana-Farber Cancer Institute, Pennsylvania State University, Penn State Health Children's Hospital, Penn State Milton S. Hershey Medical Center, University of California, San Francisco, UCSF Benioff Children's Hospital
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,650
OpenAlex ID: W2749351550