Work

A Review of Antibiotic Prophylaxis for Interventional Radiology Procedures and Identification of Antimicrobial Stewardship Opportunities

Year: 2017

Type: conference-abstract

Abstract: Antibiotics used for peri-procedural prophylaxis are dispensed by providers or nurses from automated dispensing machines in the interventional radiology (IR) suites. These antibiotics are administered without pharmacist review which skips a critical point in time for antimicrobial stewardship intervention. The purpose of this study was to evaluate antibiotic prophylaxis for IR procedures and identify opportunities for antimicrobial stewardship. All patients who underwent an IR procedure and received antibiotic prophylaxis from April 2016 to April 2017 were identified. We performed a manual chart review to determine procedure type, antibiotic prophylaxis, concomitant systemic antibiotics, and antibiotic concordance with the Society of Interventional Radiology (SIR) guidelines. There were 410 IR procedures where the patient received a single prophylactic antibiotic dose; 261 were inpatient procedures. See Table 1 for procedure and antibiotic data. There were 74 patients (18%) who concomitantly received systemic antibiotics. There were 126 cases (31%) discordant with the SIR guidelines. Reasons for discordance include prophylaxis not recommended, inappropriate antibiotic selection, or patient already receiving an antibiotic with similar spectrum of coverage. Antibiotics are frequently administered as prophylaxis for IR procedures. For many IR procedures, data to support prophylaxis is limited; however, there are opportunities for antimicrobial stewardship intervention which include optimizing antibiotic selection and withholding prophylaxis when not indicated or when patients are receiving systemic antibiotics. Table 1 CFZ, cefazolin; CRO, ceftriaxone; LVX, levofloxacin; VAN, vancomycin. Table 1 CFZ, cefazolin; CRO, ceftriaxone; LVX, levofloxacin; VAN, vancomycin. All authors: No reported disclosures.

Source: Open Forum Infectious Diseases

DOI: 10.1093/ofid/ofx163.604

Authors: Kati Shihadeh, Robert Tapia, Heather Young, Timothy C Jenkins

Institution: Denver Health Medical Center

Language: English

Topic: Antibiotic Use and Resistance

Subfield: Applied Microbiology and Biotechnology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,053