Work

Glycoprotein Ibα inhibitor (CCP-224) prevents neutrophil-platelet aggregation in sickle cell disease

Year: 2017

Type: article

Abstract: Key Points CCP-224 attenuates neutrophil-platelet aggregation in SCD patient blood. CCP-224 has the potential to prevent vaso-occlusion in SCD patients.

Source: Blood Advances

DOI: 10.1182/bloodadvances.2017006742

Authors: Maritza A. Jimenez, Enrico M. Novelli, Gray D. Shaw, Prithu Sundd

Institution: University of Pittsburgh

Language: English

Topic: Hemoglobinopathies and Related Disorders

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,800

Funder: National Heart, Lung, and Blood Institute

Awards: Platelet TSP1 Mediates Vascular Disease and pulmonary hypertension in Sickle Cell, Pulmonary arteriole occlusion by platelet-neutrophil micro-emboli in Acute Chest Syndrome, Cardiovascular Bioengineering Training Program

OpenAlex ID: W2751245620

FWCI: 1.885

Cites: 21

Cited by: 19

Related to: 10