Work

DNA Repair Mechanisms

Year: 2015

Type: article

Abstract: The integrity of human genomic DNA are constantly threatened by the action of endogenous and exogenous factors. It is estimated that more than 104 DNA lesions are occur in each mammalian cell each day. Depending on the intensity and type of the damage; cell cycle arrest, change in gene expression, stimulation of DNA repair, programmed cell death, cancer or cellular aging events may occur. To protect genomic integrity, cells have a complex network of DNA repair mechanisms. In this review, DNA repair mechanisms are discussed in general.

Source: Balıkesır Health Sciences Journal

DOI: 10.5505/bsbd.2015.52523

Authors: Elçin Latife Kurtoğlu, İbrahim Tekedereli

Language: Turkish

Topic: DNA Repair Mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W2336677088

FWCI: 0.231

Cites: 28

Cited by: 5

Related to: 10