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The Low-Affinity Binding of Second Generation Radiotracers Targeting TSPO is Associated with a Unique Allosteric Binding Site

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Year: 2017
Type: article
Source: Journal of Neuroimmune Pharmacology
DOI: 10.1007/s11481-017-9765-2
Authors: Camilo Rojas, Marigo Stathis, Jennifer M. Coughlin, Martin Pomper, Barbara S. Slusher
Institutions: Johns Hopkins University, Johns Hopkins Medicine, Czech Academy of Sciences, Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry
Language: English

Topic: Pharmacological Receptor Mechanisms and Effects
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: Johns Hopkins University, Georgia Clinical and Translational Science Alliance, National Institutes of Health, National Institute of Mental Health, National Center for Advancing Translational Sciences
Awards: G1727540074, Institute for Clinical and Translational Research, G6885418812, G7673420029, G9000075715, JHU Center for the Advancement of HIV Neurotherapeutics (JHU CAHN)
OpenAlex ID: W2751862948
FWCI: 0.679
Cites: 16
Cited by: 20
Related to: 10
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