Development of Right-hemispheric Dominance of Inferior Parietal Lobule in Proprioceptive Illusion Task
Year: 2017
Type: article
Abstract: Functional lateralization can be an indicator of brain maturation. We have consistently shown that, in the adult brain, proprioceptive processing of muscle spindle afferents generating illusory movement of the right hand activates inferior frontoparietal cortical regions in a right-side dominant manner in addition to the cerebrocerebellar motor network. Here we provide novel evidence regarding the development of the right-dominant use of the inferior frontoparietal cortical regions in humans using this task. We studied brain activity using functional magnetic resonance imaging while 60 right-handed blindfolded healthy children (8-11 years), adolescents (12-15 years), and young adults (18-23 years) (20 per group) experienced the illusion. Adult-like right-dominant use of the inferior parietal lobule (IPL) was observed in adolescents, while children used the IPL bilaterally. In contrast, adult-like lateralized cerebrocerebellar motor activation patterns were already observable in children. The right-side dominance progresses during adolescence along with the suppression of the left-sided IPL activity that emerges during childhood. Therefore, the neuronal processing implemented in the adult's right IPL during the proprioceptive illusion task is likely mediated bilaterally during childhood, and then becomes right-lateralized during adolescence at a substantially later time than the lateralized use of the cerebrocerebellar motor system for kinesthetic processing.
Source: Cerebral Cortex
Institutions: Center for Information and Neural Networks, National Institute of Information and Communications Technology, The University of Osaka, Kanazawa University, University of Fukui, Biomedical Imaging Research Center, University of Fukui, Research Center for Child Mental Development, Kanazawa University, Research Center for Child Mental Development, University of Fukui, Doshisha University
Language: English
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $5,038
Awards: G1444762020, Elucidating the Neural Basis and Development of Social Behavior through the Analysis of Inter-subjectivity, Neural mechanisms underlying the effect of parenting stress on social cognitive function, Effects of oxytocin secretion by social interaction on children's cognitive function., G2468571950, Revealing development of motor functions during golden ages, Is there shared neural underpinning of movement and social difficulties in autism spectrum disorders, Development of right inferior fronto-parietal network for bodily self-awareness, Constructive Developmental Science Based on Understanding the Process from Neuro-Dynamics to Social Interaction
OpenAlex ID: W2752263101