Year: 2017
Type: article
Abstract: We consider the translocation dynamics of a polymer chain forced through a nanopore by an external force on its head monomer on the trans side. For a proper theoretical treatment we generalize the iso-flux tension propagation (IFTP) theory to include friction arising from the trans side subchain. The theory reveals a complicated scenario of multiple scaling regimes depending on the configurations of the cis and the trans side subchains. In the limit of high driving forces f such that the trans subchain is strongly stretched, the theory is in excellent agreement with molecular dynamics simulations and allows an exact analytic solution for the scaling of the translocation time τ as a function of the chain length N 0 and f . In this regime the asymptotic scaling exponents for are , and . The theory reveals significant correction-to-scaling terms arising from the cis side subchain and pore friction, which lead to a very slow approach to from below as a function of increasing N 0 .
Source: Europhysics Letters (EPL)
Authors: Jalal Sarabadani, Bappa Ghosh, Srabanti Chaudhury, Tapio Ala-Nissila
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W2753535010