Work

TOR, the Gateway to Cellular Metabolism, Cell Growth, and Disease

Year: 2017

Type: article

Abstract: Michael N. Hall is this year's recipient of the Lasker Basic Medical Research Award for the identification of the target of rapamycin, TOR. TOR is a master regulator of the cell's growth and metabolic state, and its dysregulation contributes to a variety of diseases, including diabetes, obesity, neurodegenerative disorders, aging, and cancer, making the TOR pathway an attractive therapeutic target.

Source: Cell

DOI: 10.1016/j.cell.2017.08.019

Author: John Blenis

Institution: Weill Cornell Medicine

Language: English

Topic: PI3K/AKT/mTOR signaling in cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $11,400