Year: 2013
Type: dissertation
Abstract: The underlying mechanism for the origin of ultradian rhythms is not clearly understood at present. Based on a recent study from our laboratory, we have conceptualized a model for the origin of quasiperiodic ultradian rhythms in sleep-wake state. This model hypothesizes that the ultradian rhythms of sleep-wake state may be generated by a mechanism that includes the sleep-wake homeostat. The main purpose of the present study was to test the hypothesis that sleep homeostasis and sleep-wake ultradian rhythms share a common underlying mechanism. The present study has refuted that hypothesis. I conclude that: (1) the proposed model for the generation of quasiperiodic ultradian rhythms in sleep-wake state in mammals is overly simplistic in its present form, (2) the generation of ultradian rhythms in sleep-wake state probably arise from a more complex systemic interactions between the sleep-wake oscillatory network and other internal/external inputs, rather than the simple expression of sleep homeostat.
Source: TSpace (University of Toronto)
Author: Joonbum Lim
Language: English
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2754367307