Year: 2017
Type: article
Abstract: In this letter to the editor, we highlight some concerns with a recently published method to estimate gestational age at delivery from DNA methylation data. We conduct novel analyses to highlight the implications of different choices in study design and statistical methods for the prediction of phenotypes from methylation data.
Source: Clinical Epigenetics
Institutions: University of Bristol, MRC Integrative Epidemiology Unit
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,890
Awards: G1192034430, G1605161196, G1955001954, G2164340656, G235045266, Early life adversity and trajectories of cardiometabolic health, cognitive function and physical function: improving understanding of the mechanisms and potential reversibility, G2673957436, INTERpreting epigenetic signatures in STudies of Early Life Adversity (InterStELA), G3825777449, G3831911591, The Avon Longitudinal Study for Parents and Children: An international resource for population genomic and lifecourse epidemiology. Core programme support 2014-2019., G5470336846, G5562631338, G738105237, G7758688404, Mediation analysis in life course epidemiology: methodological innovation and application to studies of obesity and cardiometabolic health, G824700880, G8518790725
OpenAlex ID: W2755485038