Work

Fitting-free algorithm for efficient quantification of collagen fiber alignment in SHG imaging applications

Year: 2017

Type: article

Abstract: ranging from 0 (randomized fibers) to 1 (perfect alignment). This represents an important improvement of the technology and may bring us one step closer to utilizing the technology for various applications in real time. In addition, we present a digital image phantom-based framework for characterizing and validating the algorithm, as well as assessing the robustness of the algorithm against different perturbations.

Source: Biomedical Optics Express

DOI: 10.1364/boe.8.004609

Authors: Gunnsteinn Hall, Wenxuan Liang, Xingde Li

Institution: Johns Hopkins University

Language: English

Topic: Cell Image Analysis Techniques

Subfield: Biophysics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $1,913

Funders: National Science Foundation, National Institutes of Health, National Cancer Institute, Division of Chemical, Bioengineering, Environmental, and Transport Systems