Haematological indices as predictors of atrial fibrillation following isolated coronary artery bypass grafting, valvular surgery, or combined procedures: a systematic review with meta-analysis
Year: 2017
Type: review
Study designs: Systematic Review, Meta-Analysis
Abstract: BACKGROUND: New postoperative atrial fibrillation (POAF) is one of the most critical and common complications after cardiovascular surgery precipitating early and late morbidities. Complete blood count (CBC) is an imperative blood test in clinical practice, routinely used in the examination of cardiovascular diseases. AIM: This systematic review with meta-analysis aimed to determine the strength of evidence for evaluating the association of haematological indices in CBC tests with atrial fibrillation following isolated coronary artery bypass graft (CABG), isolated valvular surgery, or a combination of these treatments. METHODS: We conducted a meta-analysis of studies evaluating pre- and postoperative haematological indices in patients with POAF. A comprehensive subgroup analysis was performed to explore potential sources of heterogeneity. RESULTS: A literature search of all major databases retrieved 732 studies. After screening, 22 studies were analysed including a total of 6098 patients. Pooled analysis showed preoperative platelet count (PC) (weighted mean difference [WMD] = -7.07 × 10^9/L and p < 0.001), preoperative mean platelet volume (MPV) (WMD = 0.53 FL and p < 0.001), preoperative white blood cell count (WBC) (WMD = 0.130 × 10^9/L and p < 0.001), preoperative neutrophil-to-lymphocyte ratio (NLR) (WMD = 0.33 and p < 0.001), preoperative red blood cell distribution width (RDW) (WMD = 0.36% and p < 0.001), postoperative WBC (WMD = 1.36 × 10^9/L and p < 0.001), and postoperative NLR (WMD = 0.74 and p < 0.001) as associated factors with POAF. CONCLUSIONS: Haematological indices may predict the risk of POAF before surgery. These easily-performed tests should definitely be taken into account in patients undergoing isolated CABG, valvular surgery, or combined procedures.
Source: Kardiologia Polska
Authors: Alexander Weymann, Sadeq Ali-Hasan-Al-Saegh, Aron-Frederik Popov, Anton Sabashnikov, Seyed Jalil Mirhosseini, Tong Liu, Gary Tse, Mohammadreza Lotfaliani, Azam Ghanei, Luca Testa, Fabrizio D'Ascenzo, Umberto Benedetto, Hamidreza Dehghan, Leonardo Roever, Michel Pompeu Barros de Oliveira Sá, William L. Baker, Senol Yavuz, Mohamed Zeriouh, Ahmed Mashhour, Luis Nombela-Franco, Jae-Sik Jang, Lei Meng, Mengqi Gong, Abhishek J. Deshmukh, Tullio Palmerini, Cecilia Linde, Krzysztof J. Filipiak, Giuseppe Biondi-Zoccai, Hugh Calkins, Gregg W. Stone
Institutions: Carl von Ossietzky Universität Oldenburg, Royal Brompton & Harefield NHS Foundation Trust, Harefield Hospital, Shahid Sadoughi University of Medical Sciences and Health Services, Goethe University Frankfurt, University Hospital Frankfurt, University of Cologne, University Hospital Cologne, Second Hospital of Tianjin Medical University, Tianjin Medical University, Chinese University of Hong Kong, Medical University of Warsaw, IRCCS Policlinico San Donato, Azienda Ospedaliera Citta' della Salute e della Scienza di Torino, University of Turin, University of Bristol, Universidade Federal de Uberlândia, Universidade de Pernambuco, Hartford Hospital, University of Connecticut, S.B.Ü. Bursa Yüksek İhtisas Eğitim ve Araştırma Hastanesi, Hospital Clínico San Carlos, Inje University, Inje University Busan Paik Hospital, Mayo Clinic, University of Bologna, Karolinska University Hospital, Karolinska Institutet, Istituto Neurologico Mediterraneo, Sapienza University of Rome, Johns Hopkins University, Johns Hopkins Medicine, NewYork–Presbyterian Hospital, Columbia University Irving Medical Center, Columbia University
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W2757003948