Work

Peptide therapeutics from venom: Current status and potential

Year: 2017

Type: review

Abstract: Peptides are recognized as being highly selective, potent and relatively safe as potential therapeutics. Peptides isolated from the venom of different animals satisfy most of these criteria with the possible exception of safety, but when isolated as single compounds and used at appropriate concentrations, venom-derived peptides can become useful drugs. Although the number of venom-derived peptides that have successfully progressed to the clinic is currently limited, the prospects for venom-derived peptides look very optimistic. As proteomic and transcriptomic approaches continue to identify new sequences, the potential of venom-derived peptides to find applications as therapeutics, cosmetics and insecticides grows accordingly.

Source: Bioorganic & Medicinal Chemistry

DOI: 10.1016/j.bmc.2017.09.029

Authors: Michael W. Pennington, Andrzej Czerwinski, Raymond S. Norton

Institutions: Peptides International (United States), Monash University

Language: English

Topic: Venomous Animal Envenomation and Studies

Subfield: Toxicology

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,960