Work

Plasmablastic Lymphoma: Case Report of Prolonged Survival of an Advanced Human Immunodeficiency Patient and Literature Review

Year: 2017

Type: article

Abstract: . Plasmablastic lymphoma (PBL) is a rare and highly aggressive variant of diffuse large B cell lymphoma with median survival of advanced stage patients varying between 6 and 15 months in previous reports. We report here a human immunodeficiency virus-infected patient surviving over 12 years following treatment for advanced PBL with EPOCH chemotherapy and intrathecal therapy. This case highlights the potential for improved survival in PBL with intensive chemotherapy. Further, literature review suggests promising prospects utilizing novel targeted therapies to increase the rate of prolonged responses.

Source: Case Reports in Hematology

DOI: 10.1155/2017/9561013

Authors: Hind Rafei, Ehab El-Bahesh, Antoine Finianos, Min-Ling L. Liu, Geraldine P. Schechter

Institutions: George Washington University, United States Department of Veterans Affairs, Veterans Health Administration, Washington DC VA Medical Center

Language: English

Topic: Viral-associated cancers and disorders

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $870