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Predicting novel substrates for enzymes with minimal experimental effort with active learning

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Year: 2017
Type: article
Source: Metabolic Engineering
DOI: 10.1016/j.ymben.2017.09.016
Authors: Dante A. Pertusi, Matthew E. Moura, James G. Jeffryes, Siddhant Prabhu, Bradley Walters Biggs, Keith E.J. Tyo
Institutions: Northwestern University, Argonne National Laboratory
Language: English

Topic: Enzyme Catalysis and Immobilization
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences

Open Access status: bronze

Funders: National Science Foundation, Bill and Melinda Gates Foundation, Northwestern University, National Institutes of Health, National Institute of General Medical Sciences, Division of Chemical, Bioengineering, Environmental, and Transport Systems
Awards: G3646496157, G4058206224, Northwestern University - to use a computer-aided design (CAD) tool to identify new metabolic mechanisms of action in priority drugs for the developing world., Biotechnology Predoctoral Training Program
OpenAlex ID: W2761231228
FWCI: 1.228
Cites: 48
Cited by: 55
Related to: 10
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