Developmental Control Throughout the Budding Yeast Life Cycle by Jhd2, a JARID family Histone H3 Lysine 4 Demethylase
Year: 2014
Type: dissertation
Abstract: Histone H3 lysine 4 methylation (H3K4me) is a well-studied chromatin modification that is associated with active transcription; however, its physiological roles are not well understood. The importance of maintaining proper H3K4 methylation dynamics is underlined by the fact that H3K4 methyl transferases and demethylases control the balance between pluripotency and differentiation across eukaryotes, and their misregulation is associated with oncogenesis in mammals. My research contributed to the conclusion that the budding yeast JARID1 family H3K4 demethylase, encoded by
Source: TSpace (University of Toronto)
Author: Mengshu Xu
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2761966180