Genetic association with B-cell acute lymphoblastic leukemia in allogeneic transplant patients differs by age and sex
Year: 2017
Type: article
Study design: Observational Study
Abstract: Key Points IKZF1 associations with high-risk B-ALL may differ by age and sex. A novel variant on chromosome 14, rs189434316, is associated with over a 3.5-fold risk of normal cytogenetic B-ALL.
Source: Blood Advances
Authors: Alyssa I. Clay-Gilmour, Theresa Hahn, Leah M. Preus, Kenan Onel, Andrew Skol, Eric Hungate, Qianqian Zhu, Christopher A. Haiman, Daniel O. Stram, Loreall Pooler, Xin Sheng, Li Yan, Qian Liu, Qiang Hu, Song Liu, Sebastiano Battaglia, Xiaochun Zhu, AnneMarie W. Block, Sheila N. J. Sait, Ezgi Karaesmen, Abbas Rizvi, Daniel J. Weisdorf, Christine B. Ambrosone, David Tritchler, Eva Ellinghaus, David Ellinghaus, Martin Stanulla, Jacqueline Clavel, Laurent Orsi, Stephen Spellman, Marcelo C. Pasquini, Philip L. McCarthy, Lara E. Sucheston-Campbell
Institutions: Mayo Clinic, Roswell Park Comprehensive Cancer Center, The Ohio State University, Northwell Health, University of Chicago, University of Southern California, University at Buffalo, State University of New York, Medical College of Wisconsin, University of Minnesota, Christian-Albrechts-Universität zu Kiel, Medizinische Hochschule Hannover, Inserm, Sorbonne Paris Cité, Equipe de Recherche en Epidémiologie Nutritionnelle, Centre de Recherche Épidémiologie et Statistique, Université Paris Descartes
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,800
Funders: U.S. Department of Defense, U.S. Department of Health and Human Services, Amgen, Bristol-Myers Squibb, Pfizer, Astellas Pharma US, AstraZeneca, Sanofi, WellPoint, Gilead Sciences, Alexion Pharmaceuticals, Spectrum Pharmaceuticals, Celgene, HistoGenetics, Ohio State University, Karyopharm Therapeutics, University of Chicago, University of Minnesota, Novartis Pharmaceuticals Corporation, Medical College of Wisconsin, Baxalta, Jazz Pharmaceuticals, Sunesis, Atara Biotherapeutics, bluebird bio, Children’s Oncology Group, Telomere Diagnostics, Janssen Scientific Affairs, Incyte, Otsuka America, Deutsche Forschungsgemeinschaft, Astellas Pharma, Deutsche Krebshilfe, Otsuka Pharmaceutical, Exzellenzclusters Entzündungsforschung, Swedish Orphan Biovitrum, Medac, National Institutes of Health, Health Resources and Services Administration, Genentech, Onyx Pharmaceuticals, U.S. Navy, Takeda Oncology, National Heart, Lung, and Blood Institute, Office of Naval Research, National Institute of Mental Health, National Cancer Institute, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases, National Institute of Child Health and Human Development, Eunice Kennedy Shriver National Institute of Child Health and Human Development
Awards: G1104154511, G1206703408, G1225814147, G1384772222, G1399567684, G1626132361, Etiology of Alkylator-Induced Myeloid Leukemia, G1769371581, G1770367129, G1972739234, G2108949772, G215985982, Genetic susceptibility to unrelated donor stem cell transplant-related mortality, G226656, G2319830050, G2768476723, G2814340220, G301932103, G3098694425, G3148195661, G3174164616, G3339751648, G3648917238, G3695342494, G3816434386, G3847019374, G3857084119, G421865639, G4298420724, G4373273904, G4414605889, G46020690, G4914835, G4930744573, G5201190111, G5214925129, G5442330786, G5665177021, G5706912026, G6619812508, G6678493692, G6771248800, G6850693576, G7506463667, G777363952, G7792213259, G7951127393, G8122066879, G860380395, G8649229721, G870761348, G8824031917, G8872364087, G8876996369, G9000074379, G9000115110, G9000125749, G9000133408, G9000142182, G9000150487, G9000211056, G9000288902, G9000351236, A Data Resource for Blood and Marrow Transplants and Adoptive Cellular Therapy Research, G997771125
OpenAlex ID: W2762384510