Work

Development of Photoacoustic Probes for in Vivo Molecular Imaging

Year: 2017

Type: article

Abstract: Photoacoustic (PA) imaging is an emerging, non-invasive imaging modality that encompasses attributes of both optical and ultrasound imaging. Because of the combination of optical excitation and acoustic detection, PA imaging enables high contrast and high resolution within deep tissue (centimeter depths). Recent advances in PA probe development have allowed for stimulus-responsive imaging in a variety of biological models with implications for basic, translational, and clinical sciences. This perspective highlights recent progress in the development of PA probes and their application to live-animal molecular imaging.

Source: Biochemistry

DOI: 10.1021/acs.biochem.7b00888

Authors: Christopher J. Reinhardt, Jefferson Chan

Institution: University of Illinois Urbana-Champaign

Language: English

Topic: Photoacoustic and Ultrasonic Imaging

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: green

Funders: Alfred P. Sloan Foundation, National Institute of General Medical Sciences

Awards: G1019338674, G2849680769